Arthrosamid® injection for knee arthritis
Long-lasting relief from knee osteoarthritis
Arthrosamid® is an innovative, non-biodegradable hydrogel injection designed to help reduce pain and improve function in people with knee osteoarthritis. Unlike steroid or hyaluronic acid injections, Arthrosamid® remains within the joint, where it integrates with the synovial tissue and is designed to provide long-lasting pain relief.
Treatment is performed as a simple outpatient procedure, allowing you to return home the same day.
Why choose Arthrosamid®?
- Single injection treatment
- Designed to provide long-lasting pain relief
- No surgery or hospital stay
- Walk-in, walk-out procedure
Who is Arthrosamid® suitable for?
Arthrosamid® may be suitable if you:
- Have persistent knee pain caused by osteoarthritis
- Have not achieved adequate relief with physiotherapy, pain medication or previous injections
- Wish to delay or avoid knee replacement surgery where clinically appropriate
- Are looking for a longer-lasting, non-surgical treatment option
Your specialist will assess whether Arthrosamid® is the most appropriate treatment for your individual condition.
How does Arthrosamid® work?
Arthrosamid® is a soft, non-biodegradable hydrogel made from 97.5% water. Following injection, it integrates with the synovial lining of the knee joint, becoming part of the surrounding soft tissue.
Unlike steroid or hyaluronic acid injections, Arthrosamid® is designed to remain within the joint rather than being gradually absorbed by the body. By providing long-term mechanical support to the synovial tissue, it can help reduce pain and improve joint function for people with knee osteoarthritis.
What happens during treatment?
Your treatment includes:
- Review of your symptoms and any previous imaging
- Ultrasound-guided Arthrosamid® injection
- Personalised aftercare advice and guidance on returning to normal activities
The injection is performed as an outpatient procedure, allowing you to return home shortly afterwards.
Recovery
Most patients can walk immediately after the procedure.
Some mild discomfort or swelling is common during the first few days. We recommend avoiding strenuous activity for 48 hours before gradually returning to your normal routine.
Symptom improvement usually develops over several weeks and may continue to improve over the following months.
Benefits of Arthrosamid®
- Designed to provide long-lasting pain relief
- Single outpatient injection
- No surgery or hospital admission
- Quick recovery with minimal downtime
- May improve mobility and quality of life
- May help delay the need for knee replacement surgery
Clinical evidence
Arthrosamid® has been evaluated in several prospective clinical studies involving patients with knee osteoarthritis. While individual results vary, published evidence demonstrates meaningful improvements in pain and function in many patients, with benefits maintained for several years in longer-term follow-up.
Most patients experience meaningful pain relief
The ROSA study demonstrated that 73% of patients experienced a clinically meaningful improvement in knee pain following Arthrosamid® treatment. Response rates were highest in patients under 70 years of age, although many older patients also benefited.
What is the response rate of Arthrosamid®?
Percentage of patients achieving a clinically meaningful improvement in WOMAC pain score following Arthrosamid® treatment. Individual results vary.
Consistent results across multiple clinical studies
The IDA, ROSA, LUNA and DAISY studies all demonstrated clinically meaningful reductions in knee pain following Arthrosamid® injection.
Importantly, average improvements exceeded the recognised Minimum Clinically Important Difference (MCID) and, in studies with longer follow-up, benefits were maintained for up to five years.
Reproducible results from IDA, ROSA, LUNA and DAISY
Mean improvement in WOMAC pain scores reported across four prospective clinical studies. Follow-up duration and patient populations varied between studies.
Why choose Cabot Clinic?
At Cabot Clinic, Arthrosamid® is delivered as part of a comprehensive specialist musculoskeletal service.
- Consultant-led assessment to determine whether Arthrosamid® is the right treatment for you
- Ultrasound-guided injection for accurate placement
- Access to MRI, X-ray and ultrasound where further investigation is required
- Evidence-based treatment recommendations tailored to your individual needs
- Complete care pathway, from diagnosis and injections through to rehabilitation and surgery if required
Our aim is to ensure you receive the right treatment, at the right time, with the support of an experienced multidisciplinary team.
Frequently asked questions
How long does Arthrosamid® last?
Clinical studies have demonstrated sustained improvements in pain and function for up to five years following a single injection in some patients. Individual results vary depending on the severity of osteoarthritis and other patient factors.
Is the injection painful?
Most patients tolerate the procedure well. A local anaesthetic is used to minimise discomfort during the injection. Some temporary soreness or swelling afterwards is common and usually settles within a few days.
When will I notice an improvement?
Some patients begin to notice an improvement within a few weeks, although the full benefits may continue to develop over the following months.
Can both knees be treated?
Yes. If clinically appropriate, both knees can often be treated during the same appointment.
Will I still need knee replacement surgery?
Arthrosamid® is not a cure for knee osteoarthritis and does not prevent the condition from progressing. Some patients may eventually require knee replacement surgery, while others experience sufficient symptom relief to delay surgery for several years.
Book your consultation today and take the first step towards reducing knee pain and improving mobility
If knee arthritis is affecting your daily life, our specialist team can assess your symptoms and determine whether Arthrosamid® is an appropriate treatment option for you.
If Arthrosamid® is suitable, we will explain the procedure in detail, answer any questions you may have and arrange your treatment at a convenient time.